Beilstein J. Org. Chem.2018,14, 583–592, doi:10.3762/bjoc.14.45
stirred tank reactors for the direct conversion of the starting materials to the product. This high-yielding, multigram-scale continuous synthesis provides an opportunity to achieve increase global access to hydroxychloroquine for treatment of malaria.
Keywords: antimalarial; APImanufacturing; flow
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Graphical Abstract
Figure 1:
Commercially available antimalarial drugs.